Ibrutinib Global Patent Coverage & Expiry Overview

Track protection status across key markets to assess launch feasibility.

Start your free 7-Day Trial! Book a demo to explore our global patent data.

It is formulated by 2 pharmaceutical companies such as PHARMACYCLICS LLC, ZYDUS LIFESCIENCES. It is marketed under 2 brand names, including IMBRUVICA, IBRUTINIB. Available in 6 different strengths, such as 140MG, 70MG, 280MG and others, and administered through 3 routes including CAPSULE;ORAL, TABLET;ORAL, SUSPENSION;ORAL.

Strategic Dashboard

info

insightsStrategic Insights

Sourcing & Feasibility

check_circle API availability: autorenew Loading API feasibility...

groups Licensing: 2 potential partners

calendar_todayUS Launch window: autorenew Loading launch window...

timeline Key Patent Barrier & Expiry Timeline

autorenew Loading patent barriers...

factoryGeneric Manufacturer Snapshot

autorenew Loading manufacturers...

gavelRisk & Opportunity Summary

dangerous Risk: autorenew Loading risk analysis...
watch_later Watch: autorenew Loading watch analysis...
rocket_launch Opportunity: autorenew Loading opportunity analysis...
flag
gavel
calendar_today
calendar_today

Access Global Patent Data

Stay ahead with worldwide patent expiry and latest updates.

✓ Comprehensive global patent expiry timelines
✓ Full patent family details and status updates
Unlock Global Patents

Orange Book Drug Approval Timeline

FDA approval history for this ingredient

NDA (New Drug Application) ANDA (Generic Application)

Access Global Exclusivity and Patent Expiry Extensions

Stay ahead with worldwide patent expiry insights, exclusivity data, and latest updates.

✓ Comprehensive global patent expiry timelines
✓ Full patent family details and status updates
✓ Latest exclusivity data and extensions
Unlock Global Access

US Orange Book Patents Expiration Timeline

Key expiration dates for US patents covering this ingredient

View Global Patents Expiration Timeline

Stay ahead with worldwide patent expiry insights, market data, and research updates.

✓ Comprehensive global patent expiry timelines
✓ Full patent family details and status updates
Unlock Global Patent Timeline

Orange Book Drug Strengths

Latest drug strengths approved by FDA

Strength Route of Administration Companies Latest Approval Date

Orange Book Patents

Patents approved by the FDA for the ingredient

Patent Number Publication Date Legal Status Patent Expiry Date
{"application_id":"47903","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8952015B2","cleaned_patent_number":"8952015","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2015-02-10","legal_status":"Patented case"} US8952015B2 10 Feb, 2015 Patented case 28 Jun, 2027
{"application_id":"129449","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8476284B2","cleaned_patent_number":"8476284","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2013-07-02","legal_status":"Granted"} US8476284B2 02 Jul, 2013 Granted 28 Jun, 2027
{"application_id":"129478","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US9181257B2","cleaned_patent_number":"9181257","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2015-11-10","legal_status":"Patented case"} US9181257B2 10 Nov, 2015 Patented case 28 Jun, 2027
{"application_id":"129469","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8957079B2","cleaned_patent_number":"8957079","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2015-02-17","legal_status":"Granted"} US8957079B2 17 Feb, 2015 Granted 28 Jun, 2027
{"application_id":"129450","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8497277B2","cleaned_patent_number":"8497277","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2013-07-30","legal_status":"Patented case"} US8497277B2 30 Jul, 2013 Patented case 28 Jun, 2027
{"application_id":"2421","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US7514444B2","cleaned_patent_number":"7514444","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2009-04-07","legal_status":"Patented case"} US7514444B2 07 Apr, 2009 Patented case 28 Jun, 2027
{"application_id":"129463","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8754091B2","cleaned_patent_number":"8754091","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2014-06-17","legal_status":"Patented case"} US8754091B2 17 Jun, 2014 Patented case 28 Jun, 2027
{"application_id":"2427","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8735403B2","cleaned_patent_number":"8735403","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2014-05-27","legal_status":"Patented case"} US8735403B2 27 May, 2014 Patented case 28 Jun, 2027
{"application_id":"129457","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8703780B2","cleaned_patent_number":"8703780","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2014-04-22","legal_status":"Patented case"} US8703780B2 22 Apr, 2014 Patented case 28 Jun, 2027
{"application_id":"2425","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8697711B2","cleaned_patent_number":"8697711","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-06-28","publication_date":"2014-04-15","legal_status":"Patented case"} US8697711B2 15 Apr, 2014 Patented case 28 Jun, 2027
{"application_id":"129453","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8563563B2","cleaned_patent_number":"8563563","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2027-10-26","publication_date":"2013-10-22","legal_status":"Patented case"} US8563563B2 22 Oct, 2013 Patented case 26 Oct, 2027
{"application_id":"2422","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"8a1a340ec6f44e19b3b8","publication_number":"US8008309B2","cleaned_patent_number":"8008309","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2028-05-13","publication_date":"2011-08-30","legal_status":"Patented case"} US8008309B2 30 Aug, 2011 Patented case 13 May, 2028
{"application_id":"48179","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US11672803B2","cleaned_patent_number":"11672803","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-06-03","publication_date":"2023-06-13","legal_status":"Granted"} US11672803B2 13 Jun, 2023 Granted 03 Jun, 2031
{"application_id":"122232","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US9125889B2","cleaned_patent_number":"9125889","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2015-09-08","legal_status":"Granted"} US9125889B2 08 Sep, 2015 Granted 03 Dec, 2031
{"application_id":"48128","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US10016435B2","cleaned_patent_number":"10016435","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2018-07-10","legal_status":"Granted"} US10016435B2 10 Jul, 2018 Granted 03 Dec, 2031
{"application_id":"48172","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US10478439B2","cleaned_patent_number":"10478439","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2019-11-19","legal_status":"Patented case"} US10478439B2 19 Nov, 2019 Patented case 03 Dec, 2031
{"application_id":"48173","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US10653696B2","cleaned_patent_number":"10653696","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2020-05-19","legal_status":"Patented case"} US10653696B2 19 May, 2020 Patented case 03 Dec, 2031
{"application_id":"48174","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US10751342B2","cleaned_patent_number":"10751342","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2020-08-25","legal_status":"Granted"} US10751342B2 25 Aug, 2020 Granted 03 Dec, 2031
{"application_id":"48171","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US8754090B2","cleaned_patent_number":"8754090","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2014-06-17","legal_status":"Granted"} US8754090B2 17 Jun, 2014 Granted 03 Dec, 2031
{"application_id":"2428","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US8999999B2","cleaned_patent_number":"8999999","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2015-04-07","legal_status":"Granted"} US8999999B2 07 Apr, 2015 Granted 03 Dec, 2031
{"application_id":"2420","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US10004746B2","cleaned_patent_number":"10004746","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2018-06-26","legal_status":"Patented case"} US10004746B2 26 Jun, 2018 Patented case 03 Dec, 2031
{"application_id":"2407","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US9801881B2","cleaned_patent_number":"9801881","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2017-10-31","legal_status":"Granted"} US9801881B2 31 Oct, 2017 Granted 03 Dec, 2031
{"application_id":"2435","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US9801883B2","cleaned_patent_number":"9801883","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2017-10-31","legal_status":"Granted"} US9801883B2 31 Oct, 2017 Granted 03 Dec, 2031
{"application_id":"122235","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"79f0461b1c86428e88c2","publication_number":"US9814721B2","cleaned_patent_number":"9814721","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2031-12-03","publication_date":"2017-11-14","legal_status":"Granted"} US9814721B2 14 Nov, 2017 Granted 03 Dec, 2031
{"application_id":"48269","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US10294232B2","cleaned_patent_number":"10294232","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2019-05-21","legal_status":"Patented case"} US10294232B2 21 May, 2019 Patented case 03 Dec, 2033
{"application_id":"48268","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US10294231B2","cleaned_patent_number":"10294231","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2019-05-21","legal_status":"Granted"} US10294231B2 21 May, 2019 Granted 03 Dec, 2033
{"application_id":"108012","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US9713617B2","cleaned_patent_number":"9713617","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2017-07-25","legal_status":"Patented case"} US9713617B2 25 Jul, 2017 Patented case 03 Dec, 2033
{"application_id":"48270","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US10752634B2","cleaned_patent_number":"10752634","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2020-08-25","legal_status":"Granted"} US10752634B2 25 Aug, 2020 Granted 03 Dec, 2033
{"application_id":"48266","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US10125140B1","cleaned_patent_number":"10125140","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2018-11-13","legal_status":"Granted"} US10125140B2 13 Nov, 2018 Granted 03 Dec, 2033
{"application_id":"48265","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US10106548B2","cleaned_patent_number":"10106548","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2018-10-23","legal_status":"Granted"} US10106548B2 23 Oct, 2018 Granted 03 Dec, 2033
{"application_id":"2434","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US9725455B1","cleaned_patent_number":"9725455","drug_product_flag":"-","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2017-08-08","legal_status":"Patented case"} US9725455B2 08 Aug, 2017 Patented case 03 Dec, 2033
{"application_id":"48198","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US10961251B1","cleaned_patent_number":"10961251","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2033-12-03","publication_date":"2021-03-30","legal_status":"Granted"} US10961251B2 30 Mar, 2021 Granted 03 Dec, 2033
{"application_id":"2431","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US9540382B2","cleaned_patent_number":"9540382","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2034-02-18","publication_date":"2017-01-10","legal_status":"Patented case"} US9540382B2 10 Jan, 2017 Patented case 18 Feb, 2034
{"application_id":"2430","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"fba0fb6a046b4068ae67","publication_number":"US9296753B2","cleaned_patent_number":"9296753","drug_product_flag":"-, Y","drug_substance_flag":"-, Y","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2034-04-30","publication_date":"2016-03-29","legal_status":"Granted"} US9296753B2 29 Mar, 2016 Granted 30 Apr, 2034
{"application_id":"27983","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"44c07ad0caf34b998fbf","publication_number":"US10463668B2","cleaned_patent_number":"10463668","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2035-04-24","publication_date":"2019-11-05","legal_status":"Granted"} US10463668B2 05 Nov, 2019 Granted 24 Apr, 2035
{"application_id":"27982","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"44c07ad0caf34b998fbf","publication_number":"US9795604B2","cleaned_patent_number":"9795604","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2035-04-24","publication_date":"2017-10-24","legal_status":"Granted"} US9795604B2 24 Oct, 2017 Granted 24 Apr, 2035
{"application_id":"27984","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"44c07ad0caf34b998fbf","publication_number":"US10695350B2","cleaned_patent_number":"10695350","drug_product_flag":"-","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2035-04-24","publication_date":"2020-06-30","legal_status":"Granted"} US10695350B2 30 Jun, 2020 Granted 24 Apr, 2035
{"application_id":"94500","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"87d8270a8bb74ab785f1","publication_number":"US10213386B2","cleaned_patent_number":"10213386","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2036-09-03","publication_date":"2019-02-26","legal_status":"Granted"} US10213386B2 26 Feb, 2019 Granted 03 Sep, 2036
{"application_id":"94501","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"87d8270a8bb74ab785f1","publication_number":"US10828259B2","cleaned_patent_number":"10828259","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2036-09-03","publication_date":"2020-11-10","legal_status":"Granted"} US10828259B2 10 Nov, 2020 Granted 03 Sep, 2036
{"application_id":"2432","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"87d8270a8bb74ab785f1","publication_number":"US9655857B2","cleaned_patent_number":"9655857","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2036-09-03","publication_date":"2017-05-23","legal_status":"Granted"} US9655857B2 23 May, 2017 Granted 03 Sep, 2036
{"application_id":"94479","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"87d8270a8bb74ab785f1","publication_number":"US10010507B1","cleaned_patent_number":"10010507","drug_product_flag":"-, Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2036-09-03","publication_date":"2018-07-03","legal_status":"Patented case"} US10010507B2 03 Jul, 2018 Patented case 03 Sep, 2036
{"application_id":"164450","ingredient":"IBRUTINIB","trade_name":"IMBRUVICA","family_id":"","publication_number":"US12201690B2","cleaned_patent_number":"12201690","drug_product_flag":"Y","drug_substance_flag":"-","use_codes":["-"],"definitions":["-"],"patent_expire_date_text":"2039-06-14","publication_date":"2025-01-21","legal_status":"Granted"} US12201690B2 Formulation 21 Jan, 2025 Granted 14 Jun, 2039

Recent Clinical Trials

Latest clinical trials and research studies for this ingredient

NCT ID Title Status Phase Conditions Start Date Completion Date

API Suppliers/Manufacturer (Branded/Generic companies)

Manufacturing Locations

View Complete Supplier List

Unlock access to all suppliers of Ibrutinib

✓ Access a comprehensive list of global suppliers
✓ Get information on each supplier
Unlock Suppliers

Note: Patent expirations and exclusivity timelines are dynamic and may shift based on litigation, regulatory extensions, and maintenance filings. Regular monitoring is advised.

GreyB © 2025 Elixir. All rights reserved.